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GM mosquito trials to control dengue, chikungunya launched

Outdoor caged trials to demonstrate the efficiency of genetically modified mosquitoes to suppress wild female Aedes aegypti mosquito populations that transmit dengue, chikungunya and Zika were launched on January 23 in Dawalwadi, Badnapur, in Maharashtra’s Jalna district.


Details:
  • Based on the results of the trials, which use the Release of Insects carrying Dominant Lethal genes (RIDL) technology, and permission from Indian regulatory authorities, Gangabishan Bhikulal Investment and Trading Limited (GBIT) and Oxitec, plan to conduct open field trials in the country.
  • Laboratory-based studies have already been carried out in India since 2012 by GBIT and Oxitec and these studies have demonstrated the compatibility of Aedes aegypti mosquitoes.
Self-limiting approach:
Oxitec’s technology uses genetically modified male Aedes aegypti mosquitoes that carry a dominant lethal gene. When male GM mosquitoes mate with wild female mosquitoes the lethal gene is passed on to offspring. The lethal gene in the offspring kills the larvae before they reach adulthood, the technology is a “self-limiting approach”.
  • Since male mosquitoes do not bite humans, the release of GM males will not increase the risk of dengue, chikungunya and Zika.



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